Lutisone 50mcg Nasal Spray

Uses of Lutisone Nasal Spray

• Asthma
• Allergic rhinitis
• Inflammatory skin conditions

How does Lutisone Nasal Spray work?

It works by blocking the production of certain chemical messengers that make the skin red, swollen, and itchy due to skin conditions such as atopic eczema, allergic contact dermatitis, and

Side Effects of Lutisone Nasal Spray

Headache, Cough, Nosebleeds, Taste change, Nasopharyngitis (inflammation of the throat and nasal passages), Upper respiratory tract infection, Sinus inflammation, Stomach discomfort, Fungal infection of the oropharynx, Tremors, Palpitations, Voice change, Itching, Burning sensation

Quick Suggestions:

• You have been prescribed Fluticasone Propionate for treating itchy, red rashes, and skin irritation associated with skin conditions such as atopic eczema, allergic contact dermatitis, and psoriasis among others.
• Don't use it more often or for longer than advised by your doctor.
• Don't apply it to broken or infected areas of skin, face, eyes, or eyelids.
• Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
• If you think the area of skin you are treating has become infected you should stop using Fluticasone Propionate and consult your doctor.
• Consult your doctor if your skin condition has not improved after two weeks of treatment.

Indication of Lutisone Nasal Spray

Fluticasone Propionate belongs to a group of medicines called steroids, also known as corticosteroids. 

Pharmacology

Fluticasone propionate has anti-inflammatory and vasoconstrictor properties after topical application to the nasal mucosa. The precise mechanism of these actions is unknown, but it may involve a decrease in the number of mediator cells (basophils, leukocytes, and mast cells) at the epithelial level, eosinophils, sensory nerve sensitivity to mechanical stimuli, secretory response to cholinergic receptor stimulation, and fibroblast activity. Other methods could include capillary dilatation and permeability inhibition, lysosomal membrane stabilization, and proteolytic enzyme release prevention.

Dosage & Administration of Lutisone Nasal Spray

Adult Dose

Nasal Allergic Rhinitis:

• 2 sprays (100 mcg) in each nostril once a day, preferably in the morning.
• In some cases, 2 sprays into each nostril twice daily, not exceeding 4 sprays.

Nasal Polyps:

• 4 sprays (200 mcg) into each nostril 1-2 times daily for at least 4-6 weeks.

Child Dose

Nasal Allergic Rhinitis:

• Children over 12 years: 2 sprays (100 mcg) in each nostril once a day, preferably in the morning. In some cases, 2 sprays into each nostril twice daily, not exceeding 4 sprays.
• Children under 12 years (4-11 years): 1 spray (50 mcg) in each nostril once a day. The maximum total daily dosage should not exceed 4 sprays.

Nasal Polyps:

• Children >16 years: 4 sprays (200 mcg) into each nostril 1-2 times daily for at least 4-6 weeks.

Interaction

Before using Lutisone Nasal Spray, tell your doctor if you are taking, or have recently taken any of the following medicines:

• Medicines used to manage HIV (Ex. ritonavir, cobicistat)
• Medicine used to manage fungal infections (Ex. ketoconazole)
• Medicines used to manage asthma (Ex. theophylline)
• Medicines used to manage inflammation such as steroids (Ex. prednisolone)

Contraindications

Hypersensitivity to any of its ingredients.

Pregnancy & Lactation

Pregnancy:

• Available data on inhaled or intranasal fluticasone propionate use in pregnant women have not reported a clear association with adverse developmental outcomes.
• Fluticasone propionate crossed the placenta following subcutaneous administration to mice and rats and oral administration to rabbits.
• Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation:

• There are no available data on fluticasone propionate in human milk, its effects on breastfed children, or its effects on milk production.
• Consider the benefits of breastfeeding along with any potential adverse effects from treatment.

Precautions & Warnings

• Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma, and increased intraocular pressure have been reported.
• Systemic effects are minimal with recommended doses, but potential risks increase with larger doses.
• Use caution when administered to a nursing woman.

Storage:

• Keep all medicines out of reach of children.
• Store in a cool and dry place protected from light.